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Immune checkpoint inhibitors of PD-L1 as cancer therapeutics

Since the discovery of immune checkpoint proteins, there has been a special interest in developing antibodies that block programmed cell death 1 receptor (PD-1) and programmed cell death receptor ligand 1 (PD-L1) for a subset of cancer patients. PD-1 signaling negatively regulates T cell-mediated im...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Akinleye, Akintunde, Rasool, Zoaib
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729004/
https://ncbi.nlm.nih.gov/pubmed/31488176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0779-5
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