Ammonia-induced mitochondrial impairment is intensified by manganese co-exposure: relevance to the management of subclinical hepatic encephalopathy and cirrhosis-associated brain injury

AIM OF THE STUDY: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome ensuing from liver failure. The liver is the major site of ammonia detoxification in the human body. Hence, acute and chronic liver dysfunction can lead to hyperammonemia. Manganese (Mn) is a trace element incorporated in s...

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Detalles Bibliográficos
Publicado en:Clin Exp Hepatol
Main Authors: Heidari, Reza, Jamshidzadeh, Akram, Ommati, Mohammad Mehdi, Rashidi, Elaheh, Khodaei, Forouzan, Sadeghi, Ala, Hosseini, Arghavan, Niknahad, Hossein
Formato: Artigo
Idioma:Inglês
Publicado: Termedia Publishing House 2019
Assuntos:
Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728860/
https://ncbi.nlm.nih.gov/pubmed/31501786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceh.2019.85071
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