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In vitro and in vivo Evaluation of Succinic Acid-Substituted Mesoporous Silica for Ammonia Adsorption: Potential Application in the Management of Hepatic Encephalopathy

PURPOSE: Hepatic encephalopathy (HE) is a critical situation in which liver failure affects brain function. HE could result in a state of coma and death. The liver is the main organ for ammonium ion (NH(4)(+)) metabolism. Hence, acute and/or chronic liver failure could lead to hyperammonemia. NH(4)(...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Mohammadi, Hamidreza, Heidari, Reza, Niknezhad, Seyyed Vahid, Jamshidzadeh, Akram, Farjadian, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754271/
https://ncbi.nlm.nih.gov/pubmed/33363368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S271883
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