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A G-rich motif in the lncRNA Braveheart interacts with a zinc finger transcription factor to specify the cardiovascular lineage

Long non-coding RNAs (lncRNAs) are an emerging class of transcripts that can modulate gene expression; however, their mechanisms of action remain poorly understood. Here, we experimentally determine the secondary structure of Braveheart (Bvht) using chemical probing methods and show this ~590nt tran...

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Publicado en:Mol Cell
Autores principales: Xue, Zhihong, Hennelly, Scott, Doyle, Boryana, Gulati, Arune A., Novikova, Irina V., Sanbonmatsu, Karissa Y., Boyer, Laurie A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728430/
https://ncbi.nlm.nih.gov/pubmed/27618485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.08.010
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