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Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex

The Mycobacterium tuberculosis complex (MTBC) members display different host-specificities and virulence phenotypes. Here, we have performed a comprehensive RNAseq and methylome analysis of the main clades of the MTBC and discovered unique transcriptional profiles. The majority of genes differential...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Chiner-Oms, Álvaro, Berney, Michael, Boinett, Christine, González-Candelas, Fernando, Young, Douglas B., Gagneux, Sebastien, Jacobs, William R., Parkhill, Julian, Cortes, Teresa, Comas, Iñaki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728331/
https://ncbi.nlm.nih.gov/pubmed/31488832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11948-6
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