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Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads
Transient, regulated binding of globular protein domains to Short Linear Motifs (SLiMs) in disordered regions of other proteins drives cellular signaling. Mapping the energy landscapes of these interactions is essential for deciphering and perturbing signaling networks but is challenging due to thei...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6728138/ https://ncbi.nlm.nih.gov/pubmed/31282865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40499 |
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