Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads

Transient, regulated binding of globular protein domains to Short Linear Motifs (SLiMs) in disordered regions of other proteins drives cellular signaling. Mapping the energy landscapes of these interactions is essential for deciphering and perturbing signaling networks but is challenging due to thei...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Nguyen, Huy Quoc, Roy, Jagoree, Harink, Björn, Damle, Nikhil P, Latorraca, Naomi R, Baxter, Brian C, Brower, Kara, Longwell, Scott A, Kortemme, Tanja, Thorn, Kurt S, Cyert, Martha S, Fordyce, Polly Morrell
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2019
Konular:
Biochemistry and Chemical Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728138/
https://ncbi.nlm.nih.gov/pubmed/31282865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40499
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