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Untouchable genes in the human genome: identifying ideal targets for cancer treatment

BACKGROUND: Usually, genes with a higher-than-expected number of somatic mutations in tumor samples are assumed to be cancer related. We identified genes with a fewer-than-expected number of somatic mutations - “untouchable genes”. METHODS: To predict the expected number of somatic mutations, we use...

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Detalhes bibliográficos
Publicado no:Cancer Genet
Main Authors: Gorlov, Ivan. P., Gorlova, Olga Y., Amos, Christopher I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727980/
https://ncbi.nlm.nih.gov/pubmed/30803560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2019.01.005
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