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A Unique SUMO-Interacting Motif of Trx2 Is Critical for Its Mitochondrial Presequence Processing and Anti-oxidant Activity
OBJECTIVE: Mitochondrial thioredoxin 2 (Trx2) is a vital mitochondrial redox protein that mediates normal protein thiol reduction and provides electrons to peroxiredoxin 3 (Prx3) to scavenge H(2)O(2) in mitochondria. It has been widely reported that Trx2 deletion in cells or mice generates massive r...
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| Publicado no: | Front Physiol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6727865/ https://ncbi.nlm.nih.gov/pubmed/31555141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01089 |
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