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Ancient complement and lineage-specific evolution of the Sec7 ARF GEF proteins in eukaryotes

Guanine nucleotide exchange factors (GEFs) are the initiators of signaling by every regulatory GTPase, which in turn act to regulate a wide array of essential cellular processes. To date, each family of GTPases is activated by distinct families of GEFs. Bidirectional membrane trafficking is regulate...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Pipaliya, Shweta V., Schlacht, Alexander, Klinger, Christen M., Kahn, Richard A., Dacks, Joel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727740/
https://ncbi.nlm.nih.gov/pubmed/31141460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-01-0073
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