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Pinacol-Derived Chlorohydrosilane in Metal-Free Reductive Amination for the Preparation of Tertiary Alkylphenolmethyl Amines

[Image: see text] A new metal-free reductive amination protocol using a pinacol-derived chlorohydrosilane/pyridine system for the preparation of aminoalkylphenols is described. This method is selective toward iminiums derived from alkylphenol ketones under an in situ formation of a trialkoxyhydrosil...

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Bibliographic Details
Published in:Org Lett
Main Authors: Assoah, Benedicta, Veiros, Luis F., Candeias, Nuno R.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2019
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727611/
https://ncbi.nlm.nih.gov/pubmed/30767545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b00121
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