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Recent development of leucyl-tRNA synthetase inhibitors as antimicrobial agents
Aminoacyl-tRNA synthetases (aaRSs) widely exist in organisms and mediate protein synthesis. Inhibiting these synthetases can lead to the termination of protein synthesis and subsequently achieve antibacterial and antiparasitic purposes. Moreover, the structures of aaRSs found in eukaryotes have cons...
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| Publicado en: | Medchemcomm |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6727470/ https://ncbi.nlm.nih.gov/pubmed/31534653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00139e |
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