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Impact of Oxidative Lesions on the Human Telomeric G-Quadruplex

[Image: see text] Telomere attrition is closely associated with cell aging and exposure to reactive oxygen species (ROS). While oxidation products of nucleotides have been studied extensively in the past, the underlying secondary/tertiary structural changes in DNA remain poorly understood. In this w...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Bielskutė, Stasė, Plavec, Janez, Podbevšek, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727377/
https://ncbi.nlm.nih.gov/pubmed/30657306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b12748
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