Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer

BACKGROUND: Abrogation of growth factor-dependent signaling represents an effective therapeutic strategy for patients with colorectal cancer (CRC). Here we evaluated the effectiveness of targeting the epidermal growth factor (EGF) receptors HER-2 and HER-3 in the three cell lines LS513, LS1034 and S...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Conradi, Lena-Christin, Spitzner, Melanie, Metzger, Anna-Lena, Kisly, Merle, Middel, Peter, Bohnenberger, Hanibal, Gaedcke, Jochen, Ghadimi, Michael B., Liersch, Torsten, Rüschoff, Joseph, Beißbarth, Tim, König, Alexander, Grade, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727342/
https://ncbi.nlm.nih.gov/pubmed/31488078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6051-0
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