A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury

BACKGROUND: GATA3 is a dual-zinc finger transcription factor that regulates gene expression in many developing tissues. In the kidney, GATA3 is essential for ureteric bud branching, and mice without it fail to develop kidneys. In humans, autosomal dominant GATA3 mutations can cause renal aplasia as...

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Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Grigorieva, Irina V., Oszwald, Andre, Grigorieva, Elena F., Schachner, Helga, Neudert, Barbara, Ostendorf, Tammo, Floege, Jürgen, Lindenmeyer, Maja T., Cohen, Clemens D., Panzer, Ulf, Aigner, Christof, Schmidt, Alice, Grosveld, Frank, Thakker, Rajesh V., Rees, Andrew Jackson, Kain, Renate
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2019
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727249/
https://ncbi.nlm.nih.gov/pubmed/31405951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018111143
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