A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury

BACKGROUND: GATA3 is a dual-zinc finger transcription factor that regulates gene expression in many developing tissues. In the kidney, GATA3 is essential for ureteric bud branching, and mice without it fail to develop kidneys. In humans, autosomal dominant GATA3 mutations can cause renal aplasia as...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Grigorieva, Irina V., Oszwald, Andre, Grigorieva, Elena F., Schachner, Helga, Neudert, Barbara, Ostendorf, Tammo, Floege, Jürgen, Lindenmeyer, Maja T., Cohen, Clemens D., Panzer, Ulf, Aigner, Christof, Schmidt, Alice, Grosveld, Frank, Thakker, Rajesh V., Rees, Andrew Jackson, Kain, Renate
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727249/
https://ncbi.nlm.nih.gov/pubmed/31405951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018111143
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