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Prolines Affect the Nucleation Phase of Amyloid Fibrillation Reaction; Mutational Analysis of Human Stefin B
[Image: see text] Proline residues play a prominent role in protein folding and aggregation. We investigated the influence of single prolines and their combination on oligomerization and the amyloid fibrillation reaction of human stefin B (stB). The proline mutants influenced the distribution of oli...
Spremljeno u:
| Izdano u: | ACS Chem Neurosci |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2019
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6727212/ https://ncbi.nlm.nih.gov/pubmed/30924329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00621 |
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