Interaction between Oligomers of Stefin B and Amyloid-β in Vitro and in Cells

To contribute to the question of the putative role of cystatins in Alzheimer disease and in neuroprotection in general, we studied the interaction between human stefin B (cystatin B) and amyloid-β-(1–40) peptide (Aβ). Using surface plasmon resonance and electrospray mass spectrometry we were able to...

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Bibliografiska uppgifter
Huvudupphovsmän: Škerget, Katja, Taler-Verčič, Ajda, Bavdek, Andrej, Hodnik, Vesna, Čeru, Slavko, Tušek-Žnidarič, Magda, Kumm, Tiina, Pitsi, Didier, Pompe-Novak, Maruša, Palumaa, Peep, Soriano, Salvador, Kopitar-Jerala, Nataša, Turk, Vito, Anderluh, Gregor, Žerovnik, Eva
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823404/
https://ncbi.nlm.nih.gov/pubmed/19955183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024620
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