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PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension

Rationale: Glycolytic shift is implicated in the pathogenesis of pulmonary arterial hypertension (PAH). It remains unknown how glycolysis is increased and how increased glycolysis contributes to pulmonary vascular remodeling in PAH. Objectives: To determine whether increased glycolysis is caused by...

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Podrobná bibliografie
Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Kovacs, Laszlo, Cao, Yapeng, Han, Weihong, Meadows, Louise, Kovacs-Kasa, Anita, Kondrikov, Dmitry, Verin, Alexander D., Barman, Scott A., Dong, Zheng, Huo, Yuqing, Su, Yunchao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727156/
https://ncbi.nlm.nih.gov/pubmed/30817168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201812-2290OC
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