Exacerbated brain edema in a rat streptozotocin model of hyperglycemic ischemic stroke: Evidence for involvement of blood–brain barrier Na–K–Cl cotransport and Na/H exchange

Cerebral edema is exacerbated in diabetic ischemic stroke through poorly understood mechanisms. We showed previously that blood–brain barrier (BBB) Na–K–Cl cotransport (NKCC) and Na/H exchange (NHE) are major contributors to edema formation in normoglycemic ischemic stroke. Here, we investigated whe...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Yuen, Natalie Y, Chechneva, Olga V, Chen, Yi-Je, Tsai, Yi-Chen, Little, Logan K, Dang, James, Tancredi, Daniel J, Conston, Jacob, Anderson, Steven E, O’Donnell, Martha E
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727129/
https://ncbi.nlm.nih.gov/pubmed/29739261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18770844
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