Comparison of cachectic and non-cachectic sarcoma patients reveals an important role of Notch signaling in metastasis and myogenesis

Cancer-associated cachexia is a wasting syndrome that affects up to 50% of cancer patients. It is defined as unintentional weight loss ≥5% over 6 months and characterized by muscle atrophy, fatigue, and anorexia that are refractory to nutritional support. Sarcoma describes a diverse group of maligna...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Lu, Feiqi, Osei-Hwedieh, David, Mandell, Jonathan B, Morales-Restrepo, Alejandro, Hankins, Margaret L, Crasto, Jared A, Ma, Ruichen, Dinh, Vu, Watters, Rebecca J, Weiss, Kurt R
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726982/
https://ncbi.nlm.nih.gov/pubmed/31497355
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