Do Patient-derived Spheroid Culture Models Have Relevance in Chondrosarcoma Research?

BACKGROUND: In high-grade chondrosarcoma, 5-year survival is lower than 50%. Therefore, it is important that preclinical models that mimic the disease with the greatest possible fidelity are used to potentially develop new treatments. Accumulating evidence suggests that two-dimensional (2-D) cell cu...

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Veröffentlicht in:Clin Orthop Relat Res
Hauptverfasser: Ma, Ruichen, Mandell, Jonathan, Lu, Feiqi, Heim, Tanya, Schoedel, Karen, Duensing, Anette, Watters, Rebecca J., Weiss, Kurt R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2021
Schlagworte:
Selected Proceedings from the 2019 Musculoskeletal Tumor Societyguest Editor: John H. Healey Md
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899730/
https://ncbi.nlm.nih.gov/pubmed/32469486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CORR.0000000000001317
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