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The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins
Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how cells do counteract spontaneous DNA–RNA hybrids, here we screen an siRNA library covering 240 human DNA damage response (DDR) genes and select siRNAs causing DNA–RNA hybrid accumul...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726908/ https://ncbi.nlm.nih.gov/pubmed/31338941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847250 |
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