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The crystal structure of MICU2 provides insight into Ca(2+) binding and MICU1‐MICU2 heterodimer formation
The mitochondrial calcium uniporter (MCU) complex mediates the uptake of Ca(2+) into mitochondria. Its activity is regulated by a heterodimer of MICU1 and MICU2, two EF‐hand‐containing proteins that act as the main gatekeeper of the uniporter. Herein we report the crystal structure of human MICU2 at...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726906/ https://ncbi.nlm.nih.gov/pubmed/31397067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847488 |
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