Tizanidine hydrochloride exhibits a cytotoxic effect on osteosarcoma cells through the PI3K/AKT signaling pathway

OBJECTIVES: α2-adrenergic receptors are reportedly involved in cancer cell proliferation, invasion, and apoptosis through regulation of diverse molecules, which implies that it contributes to tumor progression. However, the functional significance of α2-adrenergic receptors in osteosarcoma (OS) is u...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Int Med Res
Main Authors: Xing, Xue-Wu, Sun, Yu-Fu, Zhao, Jun, Pan, Zi-Xiang, Jiang, Wen-Xue
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2019
Teme:
Pre-Clinical Research Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726809/
https://ncbi.nlm.nih.gov/pubmed/31179788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060519850395
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