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Tizanidine hydrochloride exhibits a cytotoxic effect on osteosarcoma cells through the PI3K/AKT signaling pathway

OBJECTIVES: α2-adrenergic receptors are reportedly involved in cancer cell proliferation, invasion, and apoptosis through regulation of diverse molecules, which implies that it contributes to tumor progression. However, the functional significance of α2-adrenergic receptors in osteosarcoma (OS) is u...

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Podrobná bibliografie
Vydáno v:J Int Med Res
Hlavní autoři: Xing, Xue-Wu, Sun, Yu-Fu, Zhao, Jun, Pan, Zi-Xiang, Jiang, Wen-Xue
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726809/
https://ncbi.nlm.nih.gov/pubmed/31179788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060519850395
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