Synchronous detection of circulating tumor cells in blood and disseminated tumor cells in bone marrow predicts adverse outcome in early breast cancer

PURPOSE: We examined the prognostic impact of circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) detected at the time of surgery in 742 untreated early breast cancer patients. EXPERIMENTAL DESIGN: DTCs in bone marrow were enumerated using the EPCAM-based immunomagnetic enrichment and...

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Publicat a:Clin Cancer Res
Autors principals: Magbanua, Mark Jesus M., Yau, Christina, Wolf, Denise M., Lee, Jin Sun, Chattopadhyay, Aheli, Scott, Janet H., Bowlby-Yoder, Erin, Hwang, E. Shelley, Alvarado, Michael, Ewing, Cheryl A., Delson, Amy L., van’t Veer, Laura, Esserman, Laura J., Park, John W.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726564/
https://ncbi.nlm.nih.gov/pubmed/31142502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3888
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