Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response

INTRODUCTION: The molecular biology involving neoadjuvant chemotherapy (NAC) response is poorly understood. To elucidate the impact of NAC on the breast cancer transcriptome and its association with clinical outcome, we analyzed gene expression data derived from serial tumor samples of patients with...

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Veröffentlicht in:Breast Cancer Res
Hauptverfasser: Magbanua, Mark Jesus M., Wolf, Denise M., Yau, Christina, Davis, Sarah E., Crothers, Julia, Au, Alfred, Haqq, Christopher M., Livasy, Chad, Rugo, Hope S., Esserman, Laura, Park, John W., van ’t Veer, Laura J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479083/
https://ncbi.nlm.nih.gov/pubmed/26021444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0582-3
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