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Organelle-Based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells
Aggregation of damaged or misfolded proteins is a protective mechanism against proteotoxic stress, abnormalities of which underlie many aging-related diseases. Here, we show that in asymmetrically dividing yeast cells, aggregation of cytosolic mis-folded proteins does not occur spontaneously but req...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726438/ https://ncbi.nlm.nih.gov/pubmed/25417105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.026 |
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