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Proximity labeling: spatially-resolved proteomic mapping for neurobiology

Understanding signaling pathways in neuroscience requires high-resolution maps of the underlying protein networks. Proximity-dependent biotinylation with engineered enzymes, in combination with mass spectrometry-based quantitative proteomics, has emerged as a powerful method to dissect molecular int...

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Detalles Bibliográficos
Publicado en:Curr Opin Neurobiol
Main Authors: Han, Shuo, Li, Jiefu, Ting, Alice Y
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726430/
https://ncbi.nlm.nih.gov/pubmed/29125959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2017.10.015
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