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Characterization of the Potent 5‐HT(1A /B) Receptor Antagonist and Serotonin Reuptake Inhibitor SB‐649915: Preclinical Evidence for Hastened Onset of Antidepressant/Anxiolytic Efficacy
An increase in brain serotonin (5‐HT) levels is thought to be a key mechanism of action responsible for generating antidepressant efficacy. It has been proven that selective serotonin reuptake inhibitors are effective antidepressants, but the delay to therapeutic onset of these agents is thought to...
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| Publicado no: | CNS Drug Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726354/ https://ncbi.nlm.nih.gov/pubmed/17627673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2007.00012.x |
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