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RB101‐mediated Protection of Endogenous Opioids: Potential Therapeutic Utility?
The endogenous opioids met‐ and leu‐enkephalin are inactivated by peptidases preventing the activation of opioid receptors. Inhibition of enkephalin‐degrading enzymes increases endogenous enkephalin levels and stimulates robust behavioral effects. RB101, an inhibitor of enkephalin‐degrading enzymes,...
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| Udgivet i: | CNS Drug Rev |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Inc
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726351/ https://ncbi.nlm.nih.gov/pubmed/17627672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2007.00011.x |
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