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Prediction of MMP-9 inhibitory activity of N-hydroxy-α-phenylsulfonylacetamide derivatives by pharmacophore based modeling and 3-D QSAR studies

Matrix metalloproteinase-9 (MMP-9), also known as gelatinase B, is a MMP that is strongly associated with multiple cellular processes including proliferation, angiogenesis, and metastasis. Various studies have shown that N-hydroxy-α-phenylsulfonylacetamide (HPSAs) derivatives are promising and selec...

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Detalles Bibliográficos
Publicado en:Porto Biomed J
Main Authors: Rathee, Dharmender, Lather, Viney, Dureja, Harish
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726302/
https://ncbi.nlm.nih.gov/pubmed/31595232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbj.0000000000000006
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