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Evolution of CRISPR towards accurate and efficient mammal genome engineering

The evolution of genome editing technology based on CRISPR (clustered regularly interspaced short palindromic repeats) system has led to a paradigm shift in biological research. CRISPR/Cas9-guide RNA complexes enable rapid and efficient genome editing in mammalian cells. This system induces double-s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMB Rep
Hauptverfasser: Ryu, Seuk-Min, Hur, Junseok W, Kim, Kyoungmi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726207/
https://ncbi.nlm.nih.gov/pubmed/31234957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.8.149
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