Molecular Magnetic Resonance Imaging Using a Redox-Active Iron Complex

We introduce a redox-active iron complex, Fe-PyC3A, as a biochemically responsive MRI contrast agent. Switching between Fe(3+)-PyC3A and Fe(2+)-PyC3A yields a full order of magnitude relaxivity change that is field-independent between 1.4 and 11.7 T. The oxidation of Fe(2+)-PyC3A to Fe(3+)-PyC3A by...

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發表在:J Am Chem Soc
Main Authors: Wang, Huan, Jordan, Veronica Clavijo, Ramsay, Ian A., Sojoodi, Mozhdeh, Fuchs, Bryan C., Tanabe, Kenneth K., Caravan, Peter, Gale, Eric M.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726119/
https://ncbi.nlm.nih.gov/pubmed/30874437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b00603
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