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Altered Ion Channels in an Animal Model of Charcot-Marie-Tooth Disease Type IA

How demyelination and remyelination affect the function of myelinated axons is a fundamental aspect of demyelinating diseases. We examined this issue in Trembler-J mice, a genetically authentic model of a dominantly inherited demyelinating neuropathy of humans. The K(+) channels Kv1.1 and Kv1.2 chan...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Devaux, Jérôme J., Scherer, Steven S.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726003/
https://ncbi.nlm.nih.gov/pubmed/15703401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3328-04.2005
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