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Application of Rho Antagonist to Neuronal Cell Bodies Promotes Neurite Growth in Compartmented Cultures and Regeneration of Retinal Ganglion Cell Axons in the Optic Nerve of Adult Rats

Inactivation of Rho promotes neurite growth on inhibitory substrates and axon regeneration in vivo. Here, we compared axon growth when neuronal cell bodies or injured axons were treated with a cell-permeable Rho antagonist (C3-07) in vitro and in vivo. In neurons plated in compartmented cultures, ap...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bertrand, Johanne, Winton, Matthew J., Rodriguez-Hernandez, Nieves, Campenot, Robert B., McKerracher, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725958/
https://ncbi.nlm.nih.gov/pubmed/15689547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3931-04.2005
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