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Age-Dependent Enhancement of Hippocampal Long-Term Potentiation and Impairment of Spatial Learning through the Rho-Associated Kinase Pathway in Protein Tyrosine Phosphatase Receptor Type Z-Deficient Mice

Although protein tyrosine phosphatases (PTPs) are expressed abundantly in the brain, their roles in synaptic plasticity have not been well elucidated. In this study, we have examined the physiological functions of Ptprz, which is a receptor-type PTP expressed predominantly in the brain as a chondroi...

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Publicat a:J Neurosci
Autors principals: Niisato, Kazue, Fujikawa, Akihiro, Komai, Shoji, Shintani, Takafumi, Watanabe, Eiji, Sakaguchi, Gaku, Katsuura, Goro, Manabe, Toshiya, Noda, Masaharu
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725950/
https://ncbi.nlm.nih.gov/pubmed/15689543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2565.04.2005
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