Activation of Gonadotropin-Releasing Hormone Neurons by Kisspeptin as a Neuroendocrine Switch for the Onset of Puberty

We examined the role of kisspeptin and its receptor, the G-protein-coupled receptor GPR54, in governing the onset of puberty in the mouse. In the adult male and female mouse, kisspeptin (10–100 nm) evoked a remarkably potent, long-lasting depolarization of >90% of gonadotropin-releasing hormone (...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Han, Seong-Kyu, Gottsch, Michelle L., Lee, Kathy J., Popa, Simina M., Smith, Jeremy T., Jakawich, Sonya K., Clifton, Donald K., Steiner, Robert A., Herbison, Allan E.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2005
Fag:
Behavioral/Systems/Cognitive
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725899/
https://ncbi.nlm.nih.gov/pubmed/16339030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3328-05.2005
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