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Postnatal Development of an Estradiol-Kisspeptin Positive Feedback Mechanism Implicated in Puberty Onset

The regulation of GnRH neurons by kisspeptin is critical for normal puberty onset in mammals. In the rodent the kisspeptin neurons innervating GnRH neurons are thought to reside in the rostral periventricular area of the third ventricle (RP3V). Using kisspeptin immunocytochemistry we show that kissp...

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Autors principals: Clarkson, Jenny, Boon, Wah Chin, Simpson, Evan R., Herbison, Allan E.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703539/
https://ncbi.nlm.nih.gov/pubmed/19299459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1733
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