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Dopamine Depletion Does Not Protect against Acute 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Toxicity In Vivo

Dopamine (DA) has been postulated to play a role in the loss of dopaminergic substantia nigra (SN) neurons in Parkinson's disease because of its propensity to oxidize and form quinones and other reactive oxygen species that can alter cellular function. Moreover, DA depletion can attenuate dopam...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Hasbani, Daphne M., Perez, Francisco A., Palmiter, Richard D., O'Malley, Karen L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725707/
https://ncbi.nlm.nih.gov/pubmed/16221852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0130-05.2005
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