Regulation of Dendritic Spine Morphogenesis by Insulin Receptor Substrate 53, a Downstream Effector of Rac1 and Cdc42 Small GTPases

The small GTPases Rac1 and Cdc42 are key regulators of the morphogenesis of actin-rich dendritic spines in neurons. However, little is known about how activated Rac1/Cdc42 regulates dendritic spines. Insulin receptor substrate 53 (IRSp53), which is highly expressed in the postsynaptic density (PSD),...

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Pubblicato in:J Neurosci
Autori principali: Choi, Jeonghoon, Ko, Jaewon, Racz, Bence, Burette, Alain, Lee, Jae-Ran, Kim, Seho, Na, Moonseok, Lee, Hyun Woo, Kim, Karam, Weinberg, Richard J., Kim, Eunjoon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725612/
https://ncbi.nlm.nih.gov/pubmed/15673667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3212-04.2005
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