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Specific Modulation of Na(+) Channels in Hippocampal Neurons by Protein Kinase Cϵ

Acetylcholine binding to muscarinic acetylcholine receptors activates G-proteins, phospholipase C, and protein kinase C (PKC), which phosphorylates brain Na(+) channels and reduces peak Na(+) current in hippocampal neurons. Because multiple PKC isozymes with different regulatory properties are expre...

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書目詳細資料
發表在:J Neurosci
Main Authors: Chen, Yuan, Cantrell, Angela R., Messing, Robert O., Scheuer, Todd, Catterall, William A.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725492/
https://ncbi.nlm.nih.gov/pubmed/15647496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4089-04.2005
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