FasL (CD95L/APO-1L) Resistance of Neurons Mediated by Phosphatidylinositol 3-Kinase-Akt/Protein Kinase B-Dependent Expression of Lifeguard/Neuronal Membrane Protein 35

The contribution of Fas (CD95/APO-1) to cell death mechanisms of differentiated neurons is controversially discussed. Rat cerebellar granule neurons (CGNs) express high levels of Fas in vitro but are resistant to FasL (CD95L/APO-1L/CD178)-induced apoptosis. We here show that this resistance was medi...

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Publicat a:J Neurosci
Autors principals: Beier, Christoph P., Wischhusen, Jörg, Gleichmann, Marc, Gerhardt, Ellen, Pekanovic, Ana, Krueger, Andreas, Taylor, Verdon, Suter, Ueli, Krammer, Peter H., Endres, Matthias, Weller, Michael, Schulz, Jörg B.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
Matèries:
Neurobiology of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725360/
https://ncbi.nlm.nih.gov/pubmed/16033886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1700-05.2005
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