A Uniquely Selective Inhibitor of the Mammalian Fetal Neuromuscular Nicotinic Acetylcholine Receptor

We have purified and characterized a novel conotoxin from the venom of Conus obscurus, which has the unique property of selectively and potently inhibiting the fetal form of the mammalian neuromuscular nicotinic acetylcholine receptor (nAChR) (α1β1γδ-subunits). Although this conotoxin, αA-conotoxin...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Teichert, Russell W., Rivier, Jean, Torres, Josep, Dykert, John, Miller, Charleen, Olivera, Baldomero M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
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Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725330/
https://ncbi.nlm.nih.gov/pubmed/15659611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4065-04.2005
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