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Transient Receptor Potential Vanilloid Subtype 1 Mediates Cell Death of Mesencephalic Dopaminergic Neurons In Vivo and In Vitro

Intranigral injection of the transient receptor potential vanilloid subtype 1 (TRPV1; also known as VR1) agonist capsaicin (CAP) into the rat brain, or treatment of rat mesencephalic cultures with CAP, resulted in cell death of dopaminergic (DA) neurons, as visualized by immunocytochemistry. This in...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Kim, Sang R., Lee, Da Y., Chung, Eun S., Oh, Uh T., Kim, Seung U., Jin, Byung K.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725326/
https://ncbi.nlm.nih.gov/pubmed/15659603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4166-04.2005
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