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Transient Receptor Potential Vanilloid Subtype 1 Mediates Cell Death of Mesencephalic Dopaminergic Neurons In Vivo and In Vitro

Intranigral injection of the transient receptor potential vanilloid subtype 1 (TRPV1; also known as VR1) agonist capsaicin (CAP) into the rat brain, or treatment of rat mesencephalic cultures with CAP, resulted in cell death of dopaminergic (DA) neurons, as visualized by immunocytochemistry. This in...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Kim, Sang R., Lee, Da Y., Chung, Eun S., Oh, Uh T., Kim, Seung U., Jin, Byung K.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725326/
https://ncbi.nlm.nih.gov/pubmed/15659603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4166-04.2005
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