How Stress and Fluoxetine Modulate Serotonin 2C Receptor Pre-mRNA Editing

In two inbred strains of mice, C57BL/6 and 129Sv, the majority of forebrain neocortical pre-mRNA encoding the serotonin 2C (5-HT(2C)) receptor is altered by adenosine-to-inosine editing. As a result, >60% of all mRNAs encode receptors with reduced constitutive and agonist-stimulated activity. How...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Englander, Michael T., Dulawa, Stephanie C., Bhansali, Punita, Schmauss, Claudia
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725319/
https://ncbi.nlm.nih.gov/pubmed/15659601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3895-04.2005
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