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The roles of phospholipase C activation and alternative ADAR1 and ADAR2 pre-mRNA splicing in modulating serotonin 2C-receptor editing in vivo

The serotonin 2C receptor (5-HT2CR), a Gq-protein-coupled neurotransmitter receptor, exists in multiple isoforms that result from RNA editing of five exonic adenosines that are converted to inosines. In the adult brain, editing of 5-HT2C pre-mRNA exhibits remarkable plasticity in response to environ...

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Bibliografische gegevens
Hoofdauteurs: Schmauss, Claudia, Zimnisky, Ross, Mehta, Mukti, Shapiro, Lauren P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924537/
https://ncbi.nlm.nih.gov/pubmed/20651031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2188110
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