The Slow Afterhyperpolarization in Hippocampal CA1 Neurons Covaries with Spatial Learning Ability in Aged Fisher 344 Rats

Rodents commonly exhibit age-related impairments in spatial learning tasks, deficits widely thought to reflect cellular or synaptic dysfunction in the hippocampus. Using whole-cell recordings, we examined the afterhyperpolarization (AHP) in CA1 pyramidal cells in hippocampal slices from young (4-6 m...

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Vydáno v:J Neurosci
Hlavní autoři: Tombaugh, Geoffrey C., Rowe, Wayne B., Rose, Gregory M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Behavioral/Systems/Cognitive
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725166/
https://ncbi.nlm.nih.gov/pubmed/15758171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5023-04.2005
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